Rabu, 17 Juni 2009

Efficacy of Perindopril on Haemodynamic Parameters

Early arterial wave reflections increase central artery and left ventricular pressures during late systole. It has been proposed that delaying arterial wave reflections may control hypertention and prevent cardiac complications.
Both drugs induced a drecease in carotied artery PP (pulse pressure) via quite different mechanisms; a significant reduction in AWR (arterial wave reflections) following perindopril and a decrease in heart ejection variables and aortic PWV (pulse wave velocity) following atenolol.

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